{"id":10891,"date":"2021-04-23T14:54:42","date_gmt":"2021-04-23T17:54:42","guid":{"rendered":"https:\/\/portaldasaudenews.com\/?p=10891"},"modified":"2021-04-23T14:54:42","modified_gmt":"2021-04-23T17:54:42","slug":"vacina-desenvolvida-pela-oxford-contra-malaria-apresenta-77-de-eficacia","status":"publish","type":"post","link":"https:\/\/portaldasaudenews.com\/?p=10891","title":{"rendered":"Vacina desenvolvida pela Oxford contra mal\u00e1ria apresenta 77% de efic\u00e1cia"},"content":{"rendered":"

 <\/p>\n

Um estudo divulgado nesta sexta-feira (23) pela Universidade de Oxford, revelou que uma vacina contra a mal\u00e1ria mostrou efic\u00e1cia recorde durante testes realizados na segunda fase, aumentando as esperan\u00e7as de que uma das doen\u00e7as mais mortais do mundo possa ser controlada.<\/p>\n

O\u00a0imunizante, desenvolvida por Oxford e conhecido como R21, mostrou efic\u00e1cia de at\u00e9 77% em um ensaio com 450 crian\u00e7as\u00a0em Burkina Faso, pa\u00eds da \u00c1frica Ocidental, durante 12 meses. De acordo com a institui\u00e7\u00e3o, a inje\u00e7\u00e3o foi a primeira a cumprir a meta da Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS) de uma vacina contra a mal\u00e1ria com pelo menos 75% de efic\u00e1cia.<\/p>\n

“Esses s\u00e3o resultados muito empolgantes, mostrando n\u00edveis de efic\u00e1cia sem precedentes de uma vacina que foi bem tolerada em nosso programa de teste. Estamos ansiosos para o pr\u00f3ximo ensaio de Fase 3 para demonstrar dados de seguran\u00e7a e efic\u00e1cia em larga escala para uma vacina que \u00e9 muito necess\u00e1ria nesta regi\u00e3o”, disse Halidou Tinto, o principal investigador do estudo.<\/p>\n

As crian\u00e7as vacinadas tinham idades entre 5 e 17 meses. Elas foram divididas em tr\u00eas grupos, e os pesquisadores relataram que o grupo de dose mais alta tinha 77% menos probabilidade de contrair a doen\u00e7a, “e 71% no grupo de dose mais baixa, ao longo de 12 meses de acompanhamento”, informou o comunicado. Tamb\u00e9m foi observado que “n\u00e3o houve eventos adversos graves relacionados \u00e0 vacina”.<\/p>\n

Fase 3<\/span><\/h2>\n

Os pesquisadores, juntamente com os parceiros comerciais, o Serum Institute of India e a farmac\u00eautica Novavax, est\u00e3o agora recrutando volunt\u00e1rios para um ensaio de Fase 3 “para avaliar a seguran\u00e7a e efic\u00e1cia em larga escala em 4.800 crian\u00e7as, com idades entre 5 e 36 meses, em quatro pa\u00edses africanos\u201d.<\/p>\n

No futuro, a expectativa \u00e9 produzir pelo menos 200 milh\u00f5es de doses por ano, o que teria um “grande impacto na sa\u00fade p\u00fablica se o licenciamento for obtido”, destaca a universidade.<\/p>\n

A mal\u00e1ria \u00e9 uma doen\u00e7a parasit\u00e1ria transmitida pela picada de f\u00eameas do mosquito Anopheles.\u00a0\u00c9 evit\u00e1vel e trat\u00e1vel, mas estima-se que 435 mil pessoas morram por ano, sendo a maioria crian\u00e7as menores de cinco anos.<\/p>\n

A regi\u00e3o africana foi o lar de 94% de todos os casos e mortes por mal\u00e1ria em 2019, de acordo com a OMS. “A mal\u00e1ria \u00e9 uma das principais causas de mortalidade infantil na \u00c1frica”, disse Charlemagne Ou\u00e9draogo, Ministro da Sa\u00fade de Burkina Faso, em comunicado.<\/p>\n

As larvas de Anopheles stephensi est\u00e3o agora “abundantemente” em recipientes de \u00e1gua em cidades da Eti\u00f3pia. Essa esp\u00e9cie \u00e9 o principal vetor de mosquitos da mal\u00e1ria na \u00cdndia urbanaFoto: Radboud University Medical Center\/ CNN\/ Reprodu\u00e7\u00e3o<\/p>\n

“Temos apoiado os ensaios de uma s\u00e9rie de novas vacinas candidatas em Burkina Faso e esses novos dados mostram que o licenciamento de uma nova vacina contra a mal\u00e1ria muito \u00fatil poder\u00e1 acontecer nos pr\u00f3ximos anos. Essa seria uma nova ferramenta extremamente importante para controlar a mal\u00e1ria e salvando muitas vidas”. (Com CNN Brasil)<\/p>\n

*Foto: Manjurul\u00a0<\/span>|\u00a0Cr\u00e9dito:\u00a0Getty Images\/iStockphoto<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

  Um estudo divulgado nesta sexta-feira (23) pela Universidade de Oxford, revelou que uma vacina<\/p>\n","protected":false},"author":1,"featured_media":10892,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[16,31],"tags":[],"class_list":["post-10891","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mundo","category-saude-mundo"],"yoast_head":"\nVacina desenvolvida pela Oxford contra mal\u00e1ria apresenta 77% de efic\u00e1cia - Portal da Sa\u00fade News<\/title>\n<meta name=\"description\" content=\"Um estudo divulgado nesta sexta-feira pela Oxford, revelou que uma vacina contra a mal\u00e1ria mostrou efic\u00e1cia recorde durante testes.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/portaldasaudenews.com\/?p=10891\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vacina desenvolvida pela Oxford contra mal\u00e1ria apresenta 77% de efic\u00e1cia - 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